Combination of two incompatibles



May 29, 1934. c. B. STRAUCH COMBINATION OF TWO INCOMPATIBLES Filed July15, 1931 Patented May 29, 1934 UNITED STATES PATET OFIC 4 Claims.

This invention pertains to a device for the storage and application oftwo incompatible chemicals, either pure or in mixture, for medicalpurposes.

5 In medicine, two incompatible chemicals are frequently combined at theplace of application where a product of their chemical reaction producesa useful effect.

For example:

One of the two incompatibles may be an aqueous paste mixture of bariumperoxide and precipitated chalk, and the other incompatible may be anaqueous solution of a fruit acid. When the two incompatibles arecombined at the locus of application as, for instance, in a wound,nascent hydrogen peroxide will develop, which will have a useful andantiseptic action.

One incompatible may be represented by a 20 mixture of sodiumbicarbonate, suitable antiseptics and easily foaming inert substances,while the other incompatible may be composed of a similar mixturecontaining, however, tartaric acid instead of sodium bicarbonate. Thetwo mixtures are kept separated before use. When admixed at the locus ofapplication as, for instance, in the vagina, carbon dioxide willimmediately be liberated and will transform the mixture into a greatlyexpanding foam, which will carry the 30 antiseptic into every fold ofthe vaginal cavity.

The latter example is of very great practical importance. The use offoam-producing antiseptic incompatibles of the character described'andin the manner outlined assures the application of the vaginalantiseptic medicaments in .a manner whichis vastly superior toantiseptic procedures as heretofore practiced by the medical professionor in the home. The importance of vaginal antisepsis is emphasized bythe fact that 65,000 mothers die annually in the United States frominfections after childbirth. Any method of improving present modes ofsterilization of the vaginal tract will tend to reduce this terrificdeath rate.

The invention herein disclosed is primarily adapted to this foamtreatment without, however, being restricted thereto. The presentinvention will provide a woman with a simple appliance for femininehygiene without the disadvantages of the douche.

On the accompanying sheet or drawing,

Fig. 1 is a sectional view through. one embodiment of the invention.

Fig. 2 is a sectional view through one element of a second embodiment ofthe present invention.

Fig. 2a is a sectional view through the second element of the secondembodiment.

Fig. 3 is a view, partly in section and partly in elevation, of a thirdform of the invention.

Reference numeral 1 designates a collapsible container of any suitableshape and material as, for instance,'a collapsible tin tube or acollapsible rubber ball, which is filled, as indicated at 2, with one ofthe two incompatible substances. One end of container 1 is closed, asindicated at 3. The other end has a neck 4, provided with means forattaching another tube or a bored cap leading to another tube. As shownin Fig. 1, this means consists of screw threads. Bore 5 of neck 4 isclosed by plate 6, which is securely retained by threaded cap 7,provided with a central bore 8. Screw cap 7 is connected to a secondtube.9 which encloses the other incompatible 10. The connection betweencap 7 and tube 9 may be accomplished by means of 7 a rubber hose 11; tofacilitate this connection,

by stopper 12 or other suitable closure.

Tube 9 may be of any suitable material. It may be collapsible, but ispreferably made of a stiff non-collapsible material, as glass or hardrubber.

The two incompatible media, 2 and 10, are thus 5 positively maintainedout of contact with each other, since plate 6, retained in place bybored cap 7, completely separates them. In use, the patient will simplyunscrew cap 7, together with attached tube 9, remove plate 6, and willthen screw cap '7 and attached tube 9 back onto neck 4. Media 2 and 10are thus placed into communication with each other through bores 5 and8.

After removal of'closure 12, pressure exerted on container 1 will forceboth media 2 and 10 out through end 13, uniting them at the point ofapplication.

A device of this kind islimited to a'single ap plication, which is verypractical since it leaves no doubt as to the quantity to be used. Afterbe simply a flat disc, or may have any other suitable shape. Tofacilitate its removal and to indicate its presence, it may be connectedwith a thread or covered with another plate of thin material, such ascellophane, tin or rubber, which will protrude from underneath cap '7,and will be removed together with plate 6, before use. Or, such amembrane alone, or any other suitable removable closure may be used.

To eliminate the screw threads, the connecting hose 11, or even tube 9,may fit directly on neck 4. In this case, obstruction, during storage,of the passage between media 2 and 10, may be secured by kinking,clamping, twisting or by other means.

In the embodiment illustrated in Figs. 2 and 2a, reference numeralswhich also occur on Fig. 1 designate corresponding elements. The maindiiference of the second embodiment is that container 9, filled withincompatible 10, is stored separately from container 1, containing theother incompatible 2. Reference numeral 14 designates a cap which closesneck 4, and reference numeral 15 designates another cap which closesopening 16 of tube 9.

This opening may be provided with means, such as the screw threads shownin Fig. 2, for direct attachment to neck 4. This is possible when thetube 9 is made of a material, such as hard rubber or metal. In Fig. 1,the material of 9 was supposed to be glass. Therefore it was necessaryto have a separate thread-bearing part, the cap '7. The twoconstructions are interchangeable, and can be replaced by otherconnections without departing from the spirit of the invention.

In use, caps 14 and 15 are removed, and opening 16 is connected withneck 4. The device will now be like that of Fig. 1, when ready for use,and will be used as described above.

Tube 9 may be a straight tube or may be curved like a vaginal nozzle tofacilitate application. The two embodiments described are intendedmerely to illustrate the underlying principle of the present invention,without limiting the latter to the particular shapes and connectionsshown.

The aforedescribed principle may be used for three or more incompatiblesby simply providing end 13 of container 9 with means for connecting itto another tube similar to 9, which could be filled with the thirdincompatible, all three incompatibles being discharged through a commonoutlet.

Instead of using two individual connected containers, use may be made ofone long tube, as shown in Fig. 3. Such tube may be made, for instance,of rubber, tin, or paraifin paper, rolled into the shape of a pipe orcone and reinforced adjacent one end by an excess of parafiin wax.Reference numeral 1'? represents the collapsible part of the container,being provided with a closed end 18, and enclosing one incompatible 19.The reinforced part of the container is shown at 20, and this part mayact as a nozzle; Part-20 encloses the other incompatible 21. The twoparts are separated by a clamp or king or other obstruction, indicatedat 22. In use, this barrier and the stopper 23 are removed. Pressureexerted on 17 will now force both incompatibles out through 24.

It is evident from the drawing that the capacity of the collapsible partof the combination, as 1 in Fig. 1 and 17 in Fig. 3, has to be largerthan that of the non-collapsible or rigid part, as 9 in Fig. 1 and 20 inFig. 3, which part may serve simultaneously as a container and nozzle.When the volume of the collapsible part is larger than that of the rigidpart, the two incompatibles are positively forced to leave the commonopening and react together.

It is apparent that the combination described has nothing in common withcollapsible tubes having elongated necks, such as those used for nasalapplications, or an attachable nozzle, as for vaginal introduction.These nozzle tubes always consist of a single unit, filled Wholly or inpart with one medium, and unable to store two incompatibles and to unitethem for a new and useful reaction.

What I claim is: r

1. A combination storage and applicator device for two incompatiblemedicinal media, said device comprising a two part substantially tubularcontainer, said parts being disposed in longitudinal alignment, one ofsaid parts being collapsible and the other being non-collapsible, and aremovable barrier disposed between said parts.

2. A combination storage and applicator device for two incompatiblemedicinal media, said device consisting of a two part substantiallytubular container, said parts being disposed in longitudinal alignment,one of said parts being collapsible and the other being non-collapsible,said non-collapsible part being provided with an opening adapted toserve as a common outlet for the contents of the two parts, andremovable means for separating the contents of the parts from eachother.

3. A combination storage and applicator device for two incompatiblemedicinal media, said device consisting of a two part substantiallytubular container, said parts being disposed in longitudinal alignment,one of said parts being of substantially greater capacity than theother, said other part being elongated whereby it is adapted to serve asan applicator nozzle, said first-named part being collapsible incharacter, and removable means for separating the contents of the partsfrom each other.

4. A combined storage and applicator tube consisting of a collapsiblepart adapted to enclose one medicinal medium, a second elongated partextending from and constituting an extension of said first named part,said second part being of relatively reduced capacity and having areinforced wall structure whereby it is adapted to serve as anapplicator nozzle, said second part being adapted to enclose a medicinalmedium which is

